Description

1-Stearoyl-2-Linoleoylphosphatidylcholine (SLPC) is a defined, high-purity phospholipid with a specific fatty acid composition at the sn-1 and sn-2 positions of the glycerol backbone. This precise molecular structure is critical for research and development in advanced lipid-based delivery systems, where consistency and reproducibility are paramount. It is an essential material for scientists and formulators in the pharmaceutical, nutraceutical, and advanced cosmetic industries working on liposomes, lipid nanoparticles (LNPs), and other sophisticated biomimetic membranes.

Application

• Pharmaceutical Excipient & Drug Delivery: A key component in the formulation of liposomes and lipid nanoparticles (LNPs) for targeted drug delivery, mRNA vaccines, and cancer therapeutics.
• Biomembrane Research: Used as a standard or model phospholipid in biophysical studies to investigate membrane fluidity, phase behavior, and protein-lipid interactions due to its defined saturated and unsaturated fatty acid chains.
• Nutraceutical Formulations: Incorporated into high-end nutritional supplements designed for cognitive health and liver support, leveraging its role as a source of structured phosphatidylcholine.
• Cosmetic Actives Carrier: Employed in advanced cosmetic formulations to enhance the penetration and stability of active ingredients through the skin barrier.
• Cell Culture & Biotechnology: Used in serum-free media supplements and for creating defined lipid environments in cell culture applications.
• Analytical Reference Standard: Serves as a high-purity chromatographic standard for the qualification and quantification of phospholipids in complex mixtures.

Basic Information

Product Name	1-Stearoyl-2-Linoleoylphosphatidylcholine
CAS No.	27098-24-4
Molecular Formula	C46H86NO8P
Molecular Weight	812.15 g/mol
Synonyms	SLPC; 1-Octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine; Phosphatidylcholine (18:0/18:2); PC(18:0/18:2(9Z,12Z)); 3-sn-Phosphatidylcholine 1-stearoyl-2-linoleoyl; 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine; (2R)-2-[(9Z,12Z)-Octadeca-9,12-dienoyloxy]-3-(stearoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
EINECS	Contact for details

Quality Control

Our 1-Stearoyl-2-Linoleoylphosphatidylcholine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and fatty acid profile confirmation, to ensure it meets stringent specifications for research and GMP-grade applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive); allow the sealed container to reach room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0% (Area %)
Fatty Acid Composition (sn-1/sn-2)	Stearoyl (C18:0) / Linoleoyl (C18:2) confirmed
Water Content (KF)	≤ 3.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.