Description

Oxametacin is a non-steroidal anti-inflammatory drug (NSAID) belonging to the indole acetic acid derivative class, known for its potent analgesic and anti-inflammatory properties. Its primary commercial value lies in its use as a key pharmaceutical intermediate for the synthesis of advanced anti-inflammatory medications. This compound is essential for manufacturers in the pharmaceutical industry, particularly those developing treatments for conditions like arthritis and other inflammatory disorders. Oxametacin CAS NO 27035-30-9 is supplied to meet the stringent quality demands of global API and finished dosage form production.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of final active pharmaceutical ingredients (APIs) for anti-inflammatory and analgesic drugs.
• Research & Development: Serves as a reference standard and starting material in medicinal chemistry research for developing new NSAID analogs.
• Analytical Standard: Used in quality control laboratories for method development, validation, and as a certified reference material for HPLC and other analytical techniques.
• Veterinary Pharmaceuticals: Potential application in formulating anti-inflammatory treatments for animal healthcare.

Basic Information

Product Name	Oxametacin
CAS No.	27035-30-9
Molecular Formula	C20H18N2O4
Molecular Weight	350.37 g/mol
Synonyms	Oxametacine; Wy-21743; 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid carboxymethyloxime; Indomethacin oxime; Oxamethacin; Carboxymethoxime of Indomethacin
EINECS	Contact for details

Quality Control

Our Oxametacin is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material that aligns with various pharmacopeial expectations, and custom synthesis to meet specific customer specifications is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.