Description

Glibornuride CAS NO 26944-48-9 is a synthetic sulfonylurea compound recognized for its specific biological activity. This high-purity chemical intermediate is critical for research and development in the pharmaceutical sector, where precise molecular structure and consistent quality are paramount. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in metabolic disorder research and novel drug synthesis.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and intermediate in the study of sulfonylurea-based therapeutics.
• Active Pharmaceutical Ingredient (API) Synthesis: Used as a building block in the multi-step synthesis of specialized drug candidates.
• Metabolic Disorder Studies: Employed in preclinical research targeting pathways related to glucose metabolism and insulin secretion.
• Biochemical Assay Development: Utilized as a ligand or inhibitor in developing high-throughput screening assays.
• Academic & Institutional Research: Supports chemical biology and medicinal chemistry programs in universities and research institutes.
• Quality Control & Analytical Testing: Functions as a certified reference material (CRM) for HPLC, LC-MS, and NMR method validation.

Basic Information

Product Name	Glibornuride
CAS No.	26944-48-9
Molecular Formula	C18H26N2O4S
Molecular Weight	366.48 g/mol
Synonyms	1-[(2R,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-(4-methylcyclohexyl)urea; Glibornuridum; Glibornuride; Ro 6-4563; 1-(4-Methylcyclohexyl)-3-[(2R,3S,4R,5R)-3,4,5-trihydroxyoxan-2-yl]urea; 3-(4-Methylcyclohexyl)-1-[(2R,3S,4R,5R)-3,4,5-trihydroxyoxan-2-yl]urea
EINECS	Contact for details

Quality Control

Our Glibornuride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identity confirmation (IR, NMR). A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.