Description

(2As,8Aα)-Decahydro-6-[2-(3-Furyl)Ethyl]-6α,7β-Dihydroxy-2Aα,5Aβ,7-Trimethyl-2H-Naphtho[1,8-Bc]Furan-2-One is a complex, high-purity synthetic intermediate characterized by its unique fused furan-naphthalene structure. This compound matters for its role as a key chiral building block in advanced organic synthesis, enabling the construction of sophisticated molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, particularly those with steroidal or terpenoid-like frameworks.
• Asymmetric Synthesis: Utilized as a chiral synthon for constructing molecules with specific three-dimensional configurations, essential for biological activity.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore new therapeutic avenues.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial production.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in regulatory submissions.
• Academic Research: Applied in university and institutional labs for methodological development in total synthesis and natural product analog creation.

Basic Information

Product Name	(2As,8Aα)-Decahydro-6-[2-(3-Furyl)Ethyl]-6α,7β-Dihydroxy-2Aα,5Aβ,7-Trimethyl-2H-Naphtho[1,8-Bc]Furan-2-One
CAS No.	26549-00-8
Molecular Formula	C21H30O5
Molecular Weight	362.46 g/mol
Synonyms	6-[2-(3-Furyl)ethyl]-6α,7β-dihydroxy-2α,5β,7-trimethyldecahydro-2H-naphtho[1,8-bc]furan-2-one; 6α,7β-Dihydroxy-6-[2-(3-furyl)ethyl]-2α,5β,7-trimethyldecahydro-2H-naphtho[1,8-bc]furan-2-one; (2α,5β,6α,7β,8aα)-6-[2-(3-Furanyl)ethyl]decahydro-6,7-dihydroxy-2,5,7-trimethylnaphtho[1,8-bc]furan-2-one; A derivative of Stemodin; Stemodinone analog. Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our (2As,8Aα)-Decahydro-6-[2-(3-Furyl)Ethyl]-6α,7β-Dihydroxy-2Aα,5Aβ,7-Trimethyl-2H-Naphtho[1,8-Bc]Furan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.