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15β-(Acetyloxy)-13,20-Epoxy-3,11β,12α-Trihydroxy-2,16-Dioxopicrasan-21-Oic Acid Methyl Ester CAS NO 26540-72-7
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CAS No.:26540-72-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
15β-(Acetyloxy)-13,20-Epoxy-3,11β,12α-Trihydroxy-2,16-Dioxopicrasan-21-Oic Acid Methyl Ester is a complex, highly functionalized triterpenoid derivative. This compound is of significant interest as a key intermediate or reference standard in advanced pharmaceutical research and natural product chemistry. It is primarily sought by research institutions and pharmaceutical development companies working on novel therapeutic agents derived from natural product scaffolds. The intricate epoxy and acetyloxy functionalities make it a valuable building block for synthetic modification and biological activity studies.
Application
- Pharmaceutical Research Intermediate: Serves as a critical synthetic precursor or scaffold for developing new drug candidates with potential anti-inflammatory, anti-cancer, or other bioactivities.
- Reference Standard for Analytical Chemistry: Used as a high-purity standard in HPLC, LC-MS, and NMR for the identification and quantification of related natural products in complex mixtures.
- Natural Product Synthesis & Derivatization: Employed in semi-synthetic studies to create novel analogs of picrasane-type quassinoids for structure-activity relationship (SAR) exploration.
- Biochemical & Pharmacological Probes: Utilized in in-vitro and in-vivo studies to investigate specific biological pathways and mechanisms of action.
- Academic & Institutional Research: A key material for universities and research institutes conducting fundamental studies in organic synthesis and medicinal chemistry.
Basic Information
| Product Name | 15β-(Acetyloxy)-13,20-Epoxy-3,11β,12α-Trihydroxy-2,16-Dioxopicrasan-21-Oic Acid Methyl Ester |
| CAS No. | 26540-72-7 |
| Molecular Formula | C30H38O11 |
| Molecular Weight | 574.62 g/mol |
| Synonyms | Methyl 15β-acetoxy-13,20-epoxy-3,11β,12α-trihydroxy-2,16-dioxopicrasan-21-oate; 13,20-Epoxy-3,11β,12α-trihydroxy-15β-(acetyloxy)-2,16-dioxopicrasan-21-oic acid methyl ester; A derivative of Quassin or Picrasin; Aklavin intermediate (related class); Triterpenoid methyl ester; Contact for additional synonyms. |
| EINECS | Contact for details |
Quality Control
Our 15β-(Acetyloxy)-13,20-Epoxy-3,11β,12α-Trihydroxy-2,16-Dioxopicrasan-21-Oic Acid Methyl Ester is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical work.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled under appropriate laboratory conditions to maintain stability. For long-term storage, consider desiccation and an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Assay | ≥ 97% |
| Loss on Drying | ≤ 2.0% |
| Residue on Ignition | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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