Description

trans-4-Chlorocrotonic Acid is a versatile halogenated unsaturated carboxylic acid that serves as a key chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring both a reactive carboxylic acid group and a chlorinated alkene moiety, makes it invaluable for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of chiral drug candidates, particularly those requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts for asymmetric synthesis.
• Polymer Chemistry: Acts as a functional monomer for introducing reactive chlorovinyl groups into specialty polymers and coatings.
• Chemical Research: Employed in academic and industrial R&D for studying cycloaddition reactions and developing new synthetic methodologies.
• Fine Chemical Production: A building block for manufacturing complex fragrance and flavor compounds.

Basic Information

Product Name	trans-4-Chlorocrotonic Acid
CAS No.	26340-58-9
Molecular Formula	C4H5ClO2
Molecular Weight	120.53 g/mol
Synonyms	(E)-4-Chlorobut-2-enoic Acid; trans-4-Chloro-2-butenoic Acid; (2E)-4-Chloro-2-butenoic Acid; 4-Chlorocrotonic Acid; (E)-4-Chlorocrotonic Acid; 4-Chloro-trans-crotonic Acid; 4-Chloro-(E)-crotonic Acid; Crotonic acid, 4-chloro-, (E)-
EINECS	247-637-5

Quality Control

Our trans-4-Chlorocrotonic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, isomeric purity, and impurity profiles. We support our clients' regulatory needs and can provide material suitable for research and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The compound is a strong acid and moisture-sensitive; handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isomeric Purity (GC/HPLC)	≥ 99.0% (trans-isomer)
Melting Point	88 - 92 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.