Description

Ethyl4-(4-Chloro-A,A,A-Trifluoro-m-Tolylo)-4-Hxdroxy-1-Piperidinecarbxylate is a high-purity, advanced pharmaceutical intermediate with a complex piperidine-carboxylate structure. This compound is valued for its role as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel therapeutic agents, particularly for neurological and psychiatric applications.
• Active Pharmaceutical Ingredient (API) Development: Serves as a crucial building block in the research and scale-up of new drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value organic molecules for specialized applications.
• Contract Manufacturing (CMO/CDMO): Supplied to contract manufacturing organizations for the production of client-specific compounds under cGMP conditions.

Basic Information

Item	Details
Product Name	Ethyl4-(4-Chloro-A,A,A-Trifluoro-m-Tolylo)-4-Hxdroxy-1-Piperidinecarbxylate
CAS No.	26111-66-0
Molecular Formula	C15H17ClF3NO3
Molecular Weight	351.75 g/mol
Synonyms	Ethyl 4-(4-Chloro-α,α,α-trifluoro-m-tolyl)-4-hydroxypiperidine-1-carboxylate; 4-Hydroxy-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidine-1-carboxylic Acid Ethyl Ester; 1-Carbethoxy-4-(4-chloro-α,α,α-trifluoro-m-tolyl)-4-hydroxypiperidine; 4-(4-Chloro-3-trifluoromethylphenyl)-4-hydroxy-1-piperidinecarboxylic Acid Ethyl Ester; 1-Ethoxycarbonyl-4-(4-chloro-α,α,α-trifluoro-m-tolyl)-4-hydroxypiperidine; 4-Hydroxy-4-[4-chloro-3-(trifluoromethyl)phenyl]-1-piperidinecarboxylic Acid Ethyl Ester; CAS 26111-66-0
EINECS	Contact for details

Quality Control

Our Ethyl4-(4-Chloro-A,A,A-Trifluoro-m-Tolylo)-4-Hxdroxy-1-Piperidinecarbxylate is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing lot-specific results are provided with every shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to protect from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.