Description

2-Bromobutyryl Bromide is a versatile and highly reactive acyl bromide intermediate, essential for introducing the 2-bromobutyryl moiety into target molecules. Its primary value lies in its role as a key building block for the synthesis of more complex organic compounds, particularly in pharmaceutical research and fine chemical manufacturing. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as active pharmaceutical ingredient (API) synthesis and the creation of novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a brominated butyryl side chain.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where its reactivity facilitates the creation of specific molecular architectures.
• Peptide Modification & Protein Labeling: Serves as an acylating agent for modifying amino acids, peptides, or proteins, useful in biochemical research and probe development.
• Polymer Chemistry: Acts as a monomer or initiator in the synthesis of specialized polymers and functional materials.
• Organic Synthesis Reagent: Employed in various organic transformations, including Friedel-Crafts acylation and nucleophilic substitution reactions, to install functional groups.
• Ligand & Catalyst Preparation: Utilized in the preparation of complex ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Material Science Research: Used in the development of novel organic electronic materials and liquid crystals.

Basic Information

Product Name	2-Bromobutyryl Bromide
CAS No.	26074-52-2
Molecular Formula	C₄H₆Br₂O
Molecular Weight	229.90 g/mol
Synonyms	Butanoyl bromide, 2-bromo-; 2-Bromobutyric acid bromide; α-Bromobutyryl bromide; 2-Bromobutanoyl bromide; NSC 404087; Butyryl bromide, 2-bromo-; 2-Bromobutyroyl bromide
EINECS	247-432-9

Quality Control

Our 2-Bromobutyryl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by GC or HPLC and identity confirmation by FT-IR, to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and to maintain purity. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.