Description

Clometacin is a non-steroidal anti-inflammatory drug (NSAID) derivative, specifically a fenamate, known for its potent analgesic and anti-inflammatory properties. This compound is of significant interest in pharmaceutical research and development for creating new therapeutic agents. It serves as a critical pharmaceutical intermediate for synthesizing advanced drug candidates targeting inflammation and pain. Industries requiring high-purity chemical building blocks, particularly in pharmaceutical manufacturing and contract research organizations (CROs), will find this product essential for their development pipelines.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of novel non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Research & Development: Utilized in medicinal chemistry research for studying structure-activity relationships (SAR) of fenamate-class compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Biochemical Studies: Used in pharmacological research to investigate cyclooxygenase (COX) inhibition mechanisms and inflammatory pathways.

Basic Information

Product Name	Clometacin
CAS No.	25803-14-9
Molecular Formula	C16H14ClNO3
Molecular Weight	303.74 g/mol
Synonyms	Clometacin; 2-[(2,6-Dichlorophenyl)amino]benzoic Acid 2-(Dimethylamino)ethyl Ester; 2-(Dimethylamino)ethyl 2-[(2,6-Dichlorophenyl)amino]benzoate; Clometacine; BA 4164-8; NSC 113935; Fenamate Derivative
EINECS	Contact for details

Quality Control

Our Clometacin is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.