Description

(3As,4Aβ,7Aβ)-Dodecahydro-4,5-Dihydroxy-7-(2-Hydroxy-1-Oxopropoxy)-8α-Methyl-3-Methyleneazuleno[6,5-B]Furan-2-One is a complex sesquiterpene lactone derivative with significant biological activity. This high-purity compound is valued for its role as a key intermediate in advanced pharmaceutical synthesis and research into novel therapeutic agents. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing new drug candidates and bioactive molecules.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel anti-inflammatory and anticancer drug candidates.
• Biochemical Research: Used as a reference standard and probe in pharmacological studies to investigate cellular signaling pathways.
• Natural Product Synthesis: Serves as a sophisticated starting material or intermediate in the total synthesis of complex natural products.
• Preclinical Development: Employed in the development and scale-up of new active pharmaceutical ingredients (APIs) with sesquiterpene backbones.
• Academic Research: Utilized in university and institutional labs for organic chemistry and medicinal chemistry research projects.

Basic Information

Item	Details
Product Name	(3As,4Aβ,7Aβ)-Dodecahydro-4,5-Dihydroxy-7-(2-Hydroxy-1-Oxopropoxy)-8α-Methyl-3-Methyleneazuleno[6,5-B]Furan-2-One
CAS No.	25374-95-2
Molecular Formula	C20H28O7
Molecular Weight	380.43 g/mol
Synonyms	Alantolactone derivative; Isoalantolactone analog; 8α-Methyl-3-methylenazuleno[6,5-b]furan-2-one derivative; Dihydroxypropoxy alantolactone; (3aS,4aR,7aR)-Dodecahydro-4,5-dihydroxy-7-[(2-hydroxy-1-oxopropoxy)]-8a-methyl-3-methylenazuleno[6,5-b]furan-2-one; 25374-95-2; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring traceability and compliance with research and cGMP-grade material expectations where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.