Description

Zygosporind is a naturally derived fungal metabolite with demonstrated bioactive properties, primarily studied for its role in microbial growth modulation and secondary metabolite regulation. It serves as a critical reference standard and research tool for pharmaceutical development, antifungal mechanism studies, and natural product biosynthesis pathways. Researchers in academic laboratories, contract research organizations (CROs), and biopharmaceutical R&D departments rely on high-purity Zygosporind CAS NO 25374-67-8 for reproducible assay calibration and structure–activity relationship (SAR) analysis.

Application

• Reference standard for HPLC and LC-MS quantitative analysis of fungal metabolites in environmental and fermentation samples
• Tool compound in mechanistic studies of fungal sporulation and morphogenesis inhibition
• Lead molecule in antifungal drug discovery programs targeting zygomycete pathogens
• Calibration material for regulatory submissions requiring certified reference substances (CRS)
• Substrate or inhibitor in enzymatic assays investigating polyketide synthase (PKS) and nonribosomal peptide synthetase (NRPS) hybrid pathways
• Quality control benchmark for fermentation-derived natural product libraries
• Stability-indicating standard in forced degradation studies of related macrolide-like compounds

Basic Information

Product Name	Zygosporind
CAS No.	25374-67-8
Molecular Formula	C28H40O7
Molecular Weight	488.62 g/mol
Synonyms	Zygosporind; Zygosporin D; 3β,11α-Dihydroxy-16-oxo-24-nor-5α,22-cycloergosta-8(14),23E-dien-26-oic acid; NSC 127991; CI-930 analog; Ergostane-type fungal metabolite; 24-Norergosta-8(14),23-dien-26-oic acid, 3,11-dihydroxy-16-oxo-, (3β,5α,11α,22E)-; Fungal growth regulator ZD-7
EINECS	Not listed (not notified under EINECS)

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. Each batch is verified for identity (IR, HPLC retention time, and mass spectral match), purity (≥98.5% by HPLC), and absence of specified impurities (residual solvents, heavy metals, and microbial contaminants). Testing follows USP & EP general chapters where applicable, and all materials are manufactured under ISO 9001-certified quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store at 2–8 °C under inert atmosphere (nitrogen or argon) to prevent oxidation and photodegradation. Keep away from moisture and direct sunlight. Handle in a cool, dry, well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.5–101.0%
Related Substances	≤1.5% total impurities (single ≤0.5%)
Residual Solvents (by GC)	Meets ICH Q3C limits
Heavy Metals	≤10 ppm
Water Content (Karl Fischer)	≤0.5%
Specific Optical Rotation	[α]D20 = –42° to –46° (c = 1 in methanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.