Description

1-Piperazinecarboxaldehyde,4-(2-Hydroxyethyl)-(8Ci,9Ci) is a versatile heterocyclic aldehyde derivative of piperazine, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an aldehyde group and a hydroxylated side chain, makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and as a linker in prodrug design.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its piperazine core for bioactivity.
• Ligand and Chelator Preparation: Serves as a starting material for synthesizing polydentate ligands and chelating agents used in catalysis and metal ion sequestration.
• Polymer Modification: Employed to introduce functional aldehyde groups into polymer backbones for cross-linking or further chemical modification.
• Bioconjugation Chemistry: The aldehyde functionality is utilized for site-specific labeling and conjugation of biomolecules like proteins and peptides.
• Research & Development: A valuable scaffold in medicinal chemistry for constructing compound libraries and exploring structure-activity relationships (SAR).

Basic Information

Product Name	1-Piperazinecarboxaldehyde,4-(2-Hydroxyethyl)-(8Ci,9Ci)
CAS No.	25209-64-7
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	4-(2-Hydroxyethyl)piperazine-1-carbaldehyde; 1-(2-Hydroxyethyl)-4-formylpiperazine; N-Formyl-N'-(2-hydroxyethyl)piperazine; 4-(2-Hydroxyethyl)-1-piperazinecarboxaldehyde; 2-(4-Formylpiperazin-1-yl)ethanol; 1-Piperazinecarboxaldehyde, 4-(2-hydroxyethyl)-; 4-(2-Hydroxyethyl)piperazinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxaldehyde,4-(2-Hydroxyethyl)-(8Ci,9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates, including cGMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture. For long-term storage, consider using an inert atmosphere to mitigate potential oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.