Description

Bicyclo[3.1.0]Hexane-1-Carboxylic Acid is a high-purity, strained bicyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound matters for its unique three-dimensional structure, which imparts specific steric and electronic properties crucial for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, ligand design, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with unique modes of action.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers and advanced organic materials with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, exploring new cycloaddition and ring-strain release reactions.
• Fine Chemical Production: Used in the multi-step synthesis of complex fragrance and flavor compounds.

Basic Information

Product Name	Bicyclo[3.1.0]Hexane-1-Carboxylic Acid
CAS No.	25090-52-2
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	Bicyclo[3.1.0]hexane-1-carboxylic acid; 1-Bicyclo[3.1.0]hexanecarboxylic acid; 1-Carboxybicyclo[3.1.0]hexane; NSC 163022; 3-Oxabicyclo[3.1.0]hexane-6-carboxylic acid (related structure); Bicyclo(3.1.0)hexane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.0]Hexane-1-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.