Description

Glisoxepide is a synthetic sulfonylurea compound with significant pharmacological interest. This compound is valued for its role as a reference standard and active pharmaceutical ingredient (API) intermediate in research and development. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on metabolic disorders. Its well-defined chemical structure makes it a critical material for analytical and synthetic applications.

Application

• Pharmaceutical Reference Standard: Used for quality control, method validation, and calibration in analytical laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key building block in the synthesis of advanced drug candidates.
• Biochemical Research: Employed in in vitro studies to investigate mechanisms related to sulfonylurea receptors and insulin secretion.
• Metabolic Disorder Studies: Applied in preclinical research for diabetes and related metabolic syndrome pathways.
• Process Development & Scale-up: Used by process chemists to develop and optimize scalable synthetic routes for pharmaceutical production.

Basic Information

Product Name	Glisoxepide
CAS No.	25046-79-1
Molecular Formula	C18H24N2O5S
Molecular Weight	380.46 g/mol
Synonyms	1-(Hexahydro-1H-azepin-1-yl)-3-[[4-[(2-methoxyethoxy)methoxy]phenyl]sulfonyl]urea; Glisoxepid; Glysoxepide; Hoe-471; N-[(Hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-[(2-methoxyethoxy)methoxy]benzenesulfonamide; 4-[2-(Methoxyethoxy)methoxy]-N-[(hexahydro-1H-azepin-1-yl)aminocarbonyl]benzenesulfonamide
EINECS	Contact for details

Quality Control

Our Glisoxepide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other validated methods, to ensure it meets high-purity standards suitable for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.