Description

Phosphonamidous Chloride, N,p-Bis(1,1-Dimethylethyl)- is a specialized organophosphorus compound characterized by its tert-butyl substituents and reactive P-Cl bond. This chemical serves as a critical intermediate in the synthesis of complex phosphonates, phosphoramidates, and ligands for catalysis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce phosphorus-containing functional groups.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those with phosphoramidate or phosphonate moieties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and plant growth regulators where phosphorus-based chemistry is required.
• Ligand Precursor: Serves as a starting material for the preparation of specialized phosphine and phosphite ligands used in homogeneous catalysis and cross-coupling reactions.
• Polymer Modification: Employed to introduce phosphorus-containing functional groups into polymers to impart flame retardancy or modify material properties.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies in organophosphorus chemistry.
• Coordination Chemistry: Used to synthesize metal complexes and chelating agents for various industrial and laboratory applications.

Basic Information

Item	Details
Product Name	Phosphonamidous Chloride, N,p-Bis(1,1-Dimethylethyl)-
CAS No.	24411-61-8
Molecular Formula	C8H19ClNP
Molecular Weight	195.67 g/mol
Synonyms	Di-tert-butylphosphonamidous chloride; N,N-Di-tert-butylphosphoramidous chloride; (Bis(tert-butyl)amino)chlorophosphine; Di-tert-butylphosphinous amide chloride; tert-Butylphosphonamidous chloride derivative; Phosphinous amide chloride, N,N-bis(1,1-dimethylethyl)-; Chloro(di-tert-butylamino)phosphine
EINECS	Contact for details

Quality Control

Our Phosphonamidous Chloride, N,p-Bis(1,1-Dimethylethyl)- is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity. Quality is assured through a rigorous analytical protocol including NMR, HPLC, and titration methods. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.