Description

Glycolithocholic Acid, Sodium Salt is a conjugated bile acid derivative, specifically the sodium salt of glycolithocholic acid. This compound is a critical biochemical reagent and intermediate valued for its role in studying bile acid metabolism and transport mechanisms. It is primarily utilized by research institutions and pharmaceutical companies engaged in hepatobiliary research, drug discovery, and diagnostic development.

Application

• Biochemical Research: Used as a standard or substrate in studies of bile acid synthesis, conjugation, and enterohepatic circulation.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the development of therapeutics targeting liver diseases, cholesterol metabolism, and gastrointestinal disorders.
• Diagnostic Reagents: Employed in the formulation of calibration standards and controls for clinical diagnostic assays measuring bile acid profiles.
• Cell Culture & Physiology: Applied in in vitro models to investigate the effects of specific bile acids on hepatocyte function and membrane transporters.
• Metabolomics & Analytical Standards: Used as a high-purity reference material in LC-MS, HPLC, and other analytical techniques for metabolite identification and quantification.

Basic Information

Product Name	Glycolithocholic Acid, Sodium Salt
CAS No.	24404-83-9
Molecular Formula	C26H43NaO4
Molecular Weight	442.61 g/mol
Synonyms	Sodium Glycolithocholate; Glycolithocholic Acid Sodium Salt; 3α-Hydroxy-5β-cholan-24-oic Acid N-(Carboxymethyl)amide Sodium Salt; N-(3α-Hydroxy-5β-cholan-24-oyl)glycine Sodium Salt; Lithocholylglycine Sodium Salt; Sodium Lithocholylglycinate; Glycine-conjugated Lithocholic Acid Sodium Salt
EINECS	Contact for details

Quality Control

Our Glycolithocholic Acid, Sodium Salt is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.