Description

1,4-Dibenzyl-2-(Chloromethyl)Piperazine is a versatile and synthetically valuable piperazine derivative, serving as a crucial building block in advanced organic synthesis. Its bifunctional structure, featuring both a chloromethyl group and benzyl-protected amine sites, makes it an essential intermediate for constructing complex molecules with high precision. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the piperazine scaffold's prevalence in bioactive molecules.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the chloromethyl group allows for further functionalization to create diverse chemical libraries.
• Ligand and Catalyst Preparation: Employed in the preparation of specialized ligands for metal catalysis and as a building block for functionalized polymers and resins.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals used in various industrial applications.

Basic Information

Product Name	1,4-Dibenzyl-2-(Chloromethyl)Piperazine
CAS No.	24225-89-6
Molecular Formula	C19H23ClN2
Molecular Weight	314.85 g/mol
Synonyms	2-(Chloromethyl)-1,4-dibenzylpiperazine; 1,4-Dibenzyl-2-chloromethylpiperazine; 2-(Chloromethyl)-1,4-bis(phenylmethyl)piperazine; N,N-Dibenzyl-2-(chloromethyl)piperazine; Piperazine, 2-(chloromethyl)-1,4-dibenzyl-; 24225-89-6 (CAS); 1,4-Dibenzyl-2-piperazinylmethyl chloride
EINECS	Contact for details

Quality Control

Our 1,4-Dibenzyl-2-(Chloromethyl)Piperazine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive chloromethyl group, it should be stored separately from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.