Description

(R)-Piperazine-2-Carboxylic Acid CAS NO 24182-11-4 is a high-purity, non-proteinogenic amino acid derivative and a key chiral building block in organic synthesis. Its value lies in its role as a crucial intermediate for constructing complex molecules with specific stereochemistry, which is essential for biological activity. This compound is primarily needed by pharmaceutical R&D and production teams for developing active pharmaceutical ingredients (APIs), particularly in therapeutic areas like neurology and oncology, as well as by researchers in asymmetric catalysis and peptide chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Peptidomimetics & Constrained Peptides: Used to introduce conformational rigidity and specific stereocenters into peptide backbones for drug discovery.
• Asymmetric Catalyst Ligand: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective synthesis.
• Chemical Biology Research: Employed as a probe or building block in the study of enzyme mechanisms and protein-protein interactions.
• Agrochemical Synthesis: Intermediate in the production of chiral, biologically active compounds for crop protection.
• Academic & Industrial R&D: Fundamental building block for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(R)-Piperazine-2-Carboxylic Acid
CAS No.	24182-11-4
Molecular Formula	C5H10N2O2
Molecular Weight	130.15 g/mol
Synonyms	(R)-2-Piperazinecarboxylic Acid; D-Pipecolic Acid; (R)-Pipecolic Acid; (R)-Piperazine-2-carboxylic acid; (2R)-Piperazine-2-carboxylic acid; (R)-Hexahydropyridazine-2-carboxylic acid; D-Piperazine-2-carboxylic acid; (R)-PCA
EINECS	Contact for details

Quality Control

Our (R)-Piperazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.