Description

(3Ar,4S,6E,10E,11Ar)-4-Acetoxy-3A,4,5,8,9,11A-Hexahydro-6,10-Dimethyl-3-Methylenecyclodeca[B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity. This high-purity intermediate is critical for advanced organic synthesis and pharmaceutical research, offering a defined stereochemical framework for developing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of anti-inflammatory, anticancer, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly in oncology and immunology research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological potency and selectivity.
• Natural Product Synthesis: Acts as a synthetic target or intermediate in the total synthesis of complex natural sesquiterpenoids.
• Biochemical Research: Employed in studies investigating cellular signaling pathways and enzyme inhibition mechanisms.
• Reference Standard: Provides a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(3Ar,4S,6E,10E,11Ar)-4-Acetoxy-3A,4,5,8,9,11A-Hexahydro-6,10-Dimethyl-3-Methylenecyclodeca[B]Furan-2(3H)-One
CAS No.	24164-12-3
Molecular Formula	C17H22O4
Molecular Weight	290.35 g/mol
Synonyms	4-Acetoxy-3a,4,5,8,9,11a-hexahydro-6,10-dimethyl-3-methylidenecyclodeca[b]furan-2(3H)-one; 4-Acetoxy-3a,4,5,8,9,11a-hexahydro-6,10-dimethyl-3-methylenecyclodeca[b]furan-2(3H)-one; (3aR,4S,6E,10E,11aR)-4-Acetoxy-3a,4,5,8,9,11a-hexahydro-6,10-dimethyl-3-methylidenecyclodeca[b]furan-2(3H)-one; A sesquiterpene lactone acetate derivative.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥95% (by HPLC), suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality management system supports the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is light-sensitive (store away from light) and should be handled under inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.