Description

(R)-Naproxen CAS NO 23979-41-1 is the single enantiomer form of the widely used non-steroidal anti-inflammatory drug (NSAID) naproxen. This specific stereoisomer is of significant interest in pharmaceutical research and development for its distinct biological activity profile compared to the (S)-enantiomer or the racemic mixture. It is essential for organizations focused on chiral drug synthesis, enantioselective pharmacology studies, and the development of novel therapeutic agents with potentially improved efficacy or reduced side effects.

Application

• Chiral Intermediate: Serves as a critical building block in the asymmetric synthesis of more complex pharmaceutical compounds.
• Pharmacological Research: Used in preclinical and clinical studies to investigate the specific biological effects, metabolic pathways, and toxicity profile of the (R)-enantiomer.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for method development, validation, and quality control of naproxen-based products.
• Active Pharmaceutical Ingredient (API) Development: Investigated for use in the formulation of new enantiomerically pure drug products targeting inflammation and pain.
• Biochemical Studies: Utilized in research to understand enzyme-substrate interactions and stereoselective binding to biological targets like cyclooxygenase (COX) enzymes.

Basic Information

Product Name	(R)-Naproxen
CAS No.	23979-41-1
Molecular Formula	C14H14O3
Molecular Weight	230.26 g/mol
Synonyms	(R)-2-(6-Methoxynaphthalen-2-yl)propanoic acid; (R)-6-Methoxy-α-methyl-2-naphthaleneacetic acid; Dexnaproxen; R-Naproxen; (R)-Naproxen; (2R)-2-(6-Methoxynaphthalen-2-yl)propanoic acid; (R)-Naprosyn; AR-Naproxen
EINECS	Contact for details

Quality Control

Our (R)-Naproxen is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets stringent specifications for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and related substances is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The product is stable under these conditions but should be kept away from excessive heat and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Related Substances (HPLC)	Total impurities ≤1.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.