Description

(2R,5S)-2-Benzyl-5-Methylpiperazine-3,6-Dione CAS NO 23927-18-6 is a chiral piperazinedione derivative, a high-value synthetic intermediate characterized by its specific stereochemistry. This compound is critical for the development of novel pharmaceuticals and fine chemicals, where precise molecular configuration directly influences biological activity and process efficiency. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for applications in asymmetric synthesis and as a key building block for active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Asymmetric Catalyst Ligand Precursor: Used in the development of chiral ligands for metal-catalyzed reactions, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Employed in the discovery and development of novel, stereospecific pesticides and herbicides.
• Peptidomimetic Scaffold: Functions as a constrained dipeptide mimic in medicinal chemistry for designing protease inhibitors and receptor modulators.
• Fine Chemical Synthesis: Acts as a specialized intermediate for creating high-value, optically active compounds used in flavors, fragrances, and electronic chemicals.
• Academic & Process R&D: Utilized in university and industrial research laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	(2R,5S)-2-Benzyl-5-Methylpiperazine-3,6-Dione
CAS No.	23927-18-6
Molecular Formula	C12H14N2O2
Molecular Weight	218.25 g/mol
Synonyms	(2R,5S)-2-Benzyl-5-methylpiperazine-3,6-dione; (2R,5S)-2-Benzyl-5-methyl-2,5-diazabicyclo[2.2.2]octane-3,6-dione; 2-Benzyl-5-methylpiperazine-3,6-dione; (R,S)-2-Benzyl-5-methylpiperazine-3,6-dione; L-2-Benzyl-5-methylpiperazine-3,6-dione; (2R,5S)-2-Benzyl-5-methyl-3,6-piperazinedione; 23927-18-6; Benzylmethylpiperazinedione
EINECS	Contact for details

Quality Control

Our (2R,5S)-2-Benzyl-5-Methylpiperazine-3,6-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet the highest standards for research and development use. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.