Description

4-(Aminomethyl)-1-Phenethylpiperidin-4-Ol Dihydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D departments and fine chemical manufacturers engaged in the development of new therapeutic agents. The material is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency for your critical processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel central nervous system (CNS) active compounds and other specialized APIs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its piperidine-based scaffold.
• Process Chemistry Development: Serves as a starting material or advanced intermediate for scaling up synthetic routes under GMP conditions.
• Biochemical Research: Employed in the study of receptor-ligand interactions and enzyme inhibition assays.
• Custom Synthesis: A versatile building block for contract research organizations (CROs) and CDMOs producing client-specific molecules.

Basic Information

Product Name	4-(Aminomethyl)-1-Phenethylpiperidin-4-Ol Dihydrochloride
CAS No.	23804-64-0
Molecular Formula	C14H22N2O·2HCl
Molecular Weight	307.26 g/mol (free base: 234.34)
Synonyms	1-Phenethyl-4-(aminomethyl)-4-piperidinol dihydrochloride; 4-Piperidinol, 4-(aminomethyl)-1-(2-phenylethyl)-, dihydrochloride; 4-(Aminomethyl)-1-(2-phenylethyl)-4-piperidinol dihydrochloride; Norphenethyl-4-(aminomethyl)-4-piperidinol dihydrochloride; CAS 23804-64-0
EINECS	Contact for details

Quality Control

Every batch of 4-(Aminomethyl)-1-Phenethylpiperidin-4-Ol Dihydrochloride is manufactured and tested to meet stringent internal specifications suitable for research and pharmaceutical development. Our quality assurance protocol includes identity confirmation, purity assessment, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.