Description

1-(2-Pyrimidinyl)-4-[3-(3,4,5-Trimethoxyphenyl)-1,3-Dioxopropyl]Piperazine is a sophisticated heterocyclic building block and key intermediate in advanced organic synthesis. This compound matters for its role as a critical precursor in the development of novel pharmaceutical agents, particularly in medicinal chemistry research targeting specific enzyme pathways. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to synthesize potential drug candidates and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and CNS research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Tool Compound: Serves as a precursor for developing enzyme inhibitors or receptor modulators for biological testing.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex molecules with specific stereochemistry.
• Academic Research: Utilized in university and institutional labs for developing new synthetic methodologies and exploring chemical space.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.

Basic Information

Product Name	1-(2-Pyrimidinyl)-4-[3-(3,4,5-Trimethoxyphenyl)-1,3-Dioxopropyl]Piperazine
CAS No.	23776-35-4
Molecular Formula	C22H26N4O5
Molecular Weight	426.47 g/mol
Synonyms	1-(Pyrimidin-2-yl)-4-[3-(3,4,5-trimethoxyphenyl)-3-oxopropanoyl]piperazine; 4-(3-(3,4,5-Trimethoxyphenyl)-3-oxopropanoyl)-1-(pyrimidin-2-yl)piperazine; 1-(2-Pyrimidinyl)-4-(3-(3,4,5-trimethoxyphenyl)-1,3-dioxopropyl)piperazine; 23776-35-4; UNII-9V6B7T8Y4N; 9V6B7T8Y4N; 1-Pyrimidin-2-yl-4-[3-(3,4,5-trimethoxyphenyl)-3-oxopropanoyl]piperazine
EINECS	Contact for details

Quality Control

Our 1-(2-Pyrimidinyl)-4-[3-(3,4,5-Trimethoxyphenyl)-1,3-Dioxopropyl]Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC purity assay, identity confirmation, and impurity profiling. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.