Description

6-Chloropyrazine-2-Carboxylic Acid is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in serving as a key intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and functional materials who require high-purity, reliable synthetic precursors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the pyrazine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	6-Chloropyrazine-2-Carboxylic Acid
CAS No.	23688-89-3
Molecular Formula	C5H3ClN2O2
Molecular Weight	158.54 g/mol
Synonyms	2-Chloropyrazine-6-carboxylic Acid; 6-Chloro-2-pyrazinecarboxylic Acid; 2-Pyrazinecarboxylic acid, 6-chloro-; 6-Chloropyrazinecarboxylic Acid; 6-Chloro-2-carboxypyrazine; 2-Carboxy-6-chloropyrazine; 6-Chloro-pyrazine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Chloropyrazine-2-Carboxylic Acid is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request, ensuring full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.