Description

Cinnamodial CAS NO 23599-45-3 is a bioactive natural product and a sesquiterpene dialdehyde isolated from the bark of *Cinnamosma fragrans*. This compound is of significant interest due to its potent biological activities, particularly as a non-peptide antagonist of the neurokinin-1 (NK1) receptor, which is a key target in pain and inflammation pathways. It serves as a valuable reference standard and a promising lead compound for pharmaceutical research and development in the fields of neuroscience, immunology, and anti-inflammatory drug discovery.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of Cinnamodial in research, quality control (QC), and method development in analytical laboratories.
• Neuroscience Research: As a selective NK1 receptor antagonist, it is a critical tool for studying substance P-mediated pathways in pain signaling, migraine, nausea, and psychiatric disorders.
• Lead Compound in Drug Discovery: Provides a structural template for the synthesis and optimization of novel non-peptide neurokinin receptor antagonists with potential therapeutic applications.
• Biological Activity Screening: Employed in high-throughput screening (HTS) assays to evaluate anti-inflammatory, analgesic, and other pharmacological properties.
• Natural Product Chemistry: Serves as an authentic specimen for the isolation, identification, and characterization of sesquiterpenes in plant extracts and traditional medicine research.
• Academic & Institutional Research: Essential for universities and research institutes conducting studies on terpenoid biosynthesis, receptor-ligand interactions, and natural product pharmacology.

Basic Information

Product Name	Cinnamodial
CAS No.	23599-45-3
Molecular Formula	C15H20O3
Molecular Weight	248.32 g/mol
Synonyms	Cinnamodial; (1R,4S,4aS,8aS)-4-Formyl-1,4a,8-trimethyl-7-oxo-1,2,3,4,4a,5,8,8a-octahydronaphthalene-1-carbaldehyde; NSC 339586; NK1 Receptor Antagonist (Cinnamodial); Cinnamosma dialdehyde
EINECS	Contact for details

Quality Control

Our Cinnamodial is produced and handled under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0% (KF)
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.