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Tetrandrine, (Dl) CAS NO 23495-89-8
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CAS No.:23495-89-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Tetrandrine, (Dl) CAS NO 23495-89-8 is a bisbenzylisoquinoline alkaloid derived from the roots of *Stephania tetrandra* and other plants. This compound is valued for its significant pharmacological activity, serving as a key reference standard and active pharmaceutical ingredient (API) in research and development. It is primarily sought by the pharmaceutical, biotechnology, and academic research sectors for applications in cardiovascular, anti-inflammatory, and anti-cancer studies.
Application
- Pharmaceutical Reference Standard: Used for the identification, purity testing, and quantification in analytical methods like HPLC and LC-MS.
- Active Pharmaceutical Ingredient (API): Serves as a key component in the formulation of investigational drugs targeting calcium channel blockade.
- Biomedical Research: Employed in *in vitro* and *in vivo* studies to investigate its effects on hypertension, inflammation, and tumor cell proliferation.
- Natural Product Isolation & Analysis: Acts as a benchmark compound for the extraction and quality control of herbal medicines containing bisbenzylisoquinoline alkaloids.
- Biochemical Pathway Studies: Utilized to study cellular signaling pathways, particularly those involving calcium ion channels and apoptosis.
Basic Information
| Product Name | Tetrandrine, (Dl) |
| CAS No. | 23495-89-8 |
| Molecular Formula | C38H42N2O6 |
| Molecular Weight | 622.75 g/mol |
| Synonyms | Hanfangchin A; Tetrandrine (DL-form); (+/-)-Tetrandrine; NSC-77037; Fanchinin; (1S,1'S)-2,2'-Dimethyl-6,6',7,7'-tetramethoxy-1,1'-bis(1,3-benzodioxol-5-ylmethyl)-1,1',2,2'-tetrahydro-3,3'-bibenzo[a]quinolizine; 6,6',7,7'-Tetramethoxy-2,2'-dimethylberbaman |
| EINECS | Contact for details |
Quality Control
Our Tetrandrine is produced and tested under strict quality management systems. Each batch is analyzed to ensure it meets high-purity standards suitable for pharmaceutical research. Comprehensive testing includes identification, assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is kept sealed in a desiccated environment away from direct light exposure to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Loss on Drying | ≤ 2.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
| Related Substances (HPLC) | Total impurities ≤ 2.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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