Description

Ethyl 4-Hydroxy-4-[3-(Trifluoromethyl)Phenyl]Piperidine-1-Carboxylate is a high-purity, functionalized piperidine derivative that serves as a critical advanced intermediate in modern organic synthesis. Its value lies in the unique combination of a piperidine scaffold, a hydroxyl group, and a trifluoromethylphenyl moiety, enabling the construction of complex molecules with tailored properties. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Ligand and Catalyst Development: The nitrogen and oxygen functionalities make it a candidate for developing chiral ligands or organocatalysts.

Basic Information

Product Name	Ethyl 4-Hydroxy-4-[3-(Trifluoromethyl)Phenyl]Piperidine-1-Carboxylate
CAS No.	23482-34-0
Molecular Formula	C15H18F3NO3
Molecular Weight	317.31 g/mol
Synonyms	1-Carbethoxy-4-hydroxy-4-(3-trifluoromethylphenyl)piperidine; Ethyl 4-hydroxy-4-(3-trifluoromethylphenyl)-1-piperidinecarboxylate; 4-Hydroxy-4-(3-trifluoromethylphenyl)piperidine-1-carboxylic acid ethyl ester; 4-(3-Trifluoromethylphenyl)-4-hydroxypiperidine-1-carboxylic acid ethyl ester; 1-Piperidinecarboxylic acid, 4-hydroxy-4-[3-(trifluoromethyl)phenyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Hydroxy-4-[3-(Trifluoromethyl)Phenyl]Piperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.