Description

3,6-Bis-(4-Amino-Butyl)-Piperazine-2,5-Dione is a specialized piperazinedione derivative featuring terminal primary amino groups on extended alkyl chains. This unique bifunctional structure makes it a valuable building block for the synthesis of complex molecules, particularly in advanced material and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a rigid, heterocyclic core with flexible, reactive amine termini.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing polyamides, polyurethanes, and other specialty polymers with enhanced thermal stability or specific functional groups.
• Ligand Synthesis: Used to create chelating ligands for metal catalysis or metal-organic frameworks (MOFs) due to its multiple nitrogen donor atoms.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, or plant growth regulators that incorporate the piperazinedione pharmacophore.
• Bioconjugation & Linker Chemistry: The primary amine groups are ideal for conjugation reactions, making it useful for creating drug-linker systems in antibody-drug conjugates (ADCs) or diagnostic probes.
• Academic & Industrial R&D: A versatile scaffold for medicinal chemistry programs and exploratory synthesis in chemical biology.

Basic Information

Product Name	3,6-Bis-(4-Amino-Butyl)-Piperazine-2,5-Dione
CAS No.	23409-32-7
Molecular Formula	C₁₂H₂₄N₄O₂
Molecular Weight	256.35 g/mol
Synonyms	3,6-Bis(4-aminobutyl)piperazine-2,5-dione; 2,5-Piperazinedione, 3,6-bis(4-aminobutyl)-; 3,6-Di(4-aminobutyl)-2,5-piperazinedione; 1,4-Bis(4-aminobutyl)-2,5-diketopiperazine; 3,6-Bis(4-aminobutyl)-2,5-diketopiperazine (DKP derivative); 3,6-Bis(ω-aminobutyl)-2,5-piperazinedione; ABP-DKP; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3,6-Bis-(4-Amino-Butyl)-Piperazine-2,5-Dione is produced under controlled conditions to ensure high purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support development and cGMP-grade requirements, with specifications tailored to your project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.