Description

2,5-Dibromopyrazine is a versatile brominated heterocyclic building block essential for advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of pharmaceuticals and functional materials. This high-purity intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds and electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other heterocyclic drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require pyrazine-based scaffolds.
• Ligand & Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Building Block: Employed in the synthesis of organic semiconductors, conductive polymers, and liquid crystals for electronic applications.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to introduce the pyrazine ring into more complex systems.
• Chemical Research & Development: A fundamental reagent for academic and industrial research exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	2,5-Dibromopyrazine
CAS No.	23229-26-7
Molecular Formula	C4H2Br2N2
Molecular Weight	237.88 g/mol
Synonyms	2,5-Dibromo-1,4-diazine; Pyrazine, 2,5-dibromo-; 2,5-Dibromopyrazine; 1,4-Diazine, 2,5-dibromo-; NSC 403119; Dibromopyrazine; 2,5-DBP
EINECS	Contact for details

Quality Control

Our 2,5-Dibromopyrazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.