Description

Ethyl 4-[2-(Ethoxycarbonylamino)ethyl]piperazine-1-carboxylate is a versatile piperazine derivative and a key protected intermediate in advanced organic synthesis. Its structure, featuring both a urethane and a carbamate protecting group, makes it exceptionally valuable for constructing complex molecules with precise control over reactivity. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors. It serves as a critical building block for the synthesis of active pharmaceutical ingredients (APIs), fine chemicals, and novel compounds requiring a functionalized piperazine core.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly those targeting the central nervous system (CNS), as anthelmintics, or as protease inhibitors.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides where the piperazine moiety contributes to biological activity.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Chemical Research & Development: Serves as a protected precursor for introducing the 1,4-diazacyclohexane (piperazine) ring system into target molecules under controlled conditions.
• Ligand and Catalyst Development: Utilized in the creation of novel chelating ligands or organocatalysts for asymmetric synthesis and metal complexation.

Basic Information

Product Name	Ethyl 4-[2-(Ethoxycarbonylamino)ethyl]piperazine-1-carboxylate
CAS No.	23111-69-5
Molecular Formula	C12H23N3O4
Molecular Weight	273.33 g/mol
Synonyms	1-Piperazinecarboxylic acid, 4-[2-[(ethoxycarbonyl)amino]ethyl]-, ethyl ester; Ethyl 4-(2-ethoxycarbonylaminoethyl)piperazine-1-carboxylate; 4-[2-(Ethoxycarbonylamino)ethyl]-1-piperazinecarboxylic acid ethyl ester; N-Ethoxycarbonyl-N'-(2-piperazin-1-ylethyl)urea ethyl ester; UNII-6G2F4OZ0Q6; 6G2F4OZ0Q6; Ethyl 4-(2-((ethoxycarbonyl)amino)ethyl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 4-[2-(Ethoxycarbonylamino)ethyl]piperazine-1-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), impurity profile, and physical characteristics. Our quality commitment supports your R&D and scale-up processes with reliable, specification-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.