Description

Methyl 4-Hydroxybicyclo[2.2.2]Octane-1-Carboxylate is a high-purity, synthetically valuable bicyclic ester compound. It serves as a crucial chiral building block and advanced pharmaceutical intermediate for the development of novel active ingredients. This product is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, where its rigid, functionalized structure enables the synthesis of complex molecules with specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its bicyclic framework for enhanced biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis and organometallic chemistry.
• Material Science Research: A building block for novel polymers and advanced organic materials with specific structural properties.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of unique, high-value aroma chemicals.
• Academic and R&D Laboratories: A valuable compound for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	Methyl 4-Hydroxybicyclo[2.2.2]Octane-1-Carboxylate
CAS No.	23062-53-5
Molecular Formula	C10H16O3
Molecular Weight	184.23 g/mol
Synonyms	Methyl 4-hydroxybicyclo[2.2.2]octane-1-carboxylate; 4-Hydroxybicyclo[2.2.2]octane-1-carboxylic acid methyl ester; Bicyclo[2.2.2]octane-1-carboxylic acid, 4-hydroxy-, methyl ester; Methyl 4-hydroxy-1-bicyclo[2.2.2]octanecarboxylate; 1-Carbomethoxy-4-hydroxybicyclo[2.2.2]octane
EINECS	Contact for details

Quality Control

Our Methyl 4-Hydroxybicyclo[2.2.2]Octane-1-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.