Description

9-Cis Retinol is a specific geometric isomer of vitamin A, a crucial molecule in biological systems. This compound matters for its distinct biological activity and role as a key intermediate in the synthesis of specialized retinoids. It is primarily needed by research institutions and manufacturers in the pharmaceutical, nutraceutical, and advanced cosmetic industries for developing novel therapeutics and high-performance skincare formulations.

Application

• Pharmaceutical Research & Development: As a critical reference standard and active pharmaceutical ingredient (API) intermediate for novel retinoid-based drugs targeting dermatological conditions and cellular differentiation pathways.
• Advanced Cosmetic Actives: Incorporation into high-end anti-aging, skin-renewal, and photodamage repair formulations due to its specific isomer activity on skin cells.
• Nutraceutical Synthesis: Serving as a key precursor in the manufacture of specialized vitamin A supplements and fortified food ingredients.
• Biochemical Research: Used in studies of visual cycle biochemistry, cellular signaling, and gene regulation mediated by retinoid receptors.
• Reference Standard: Essential for analytical laboratories for the identification, assay, and purity testing of retinoid compounds via HPLC, GC, or LC-MS methods.

Basic Information

Product Name	9-Cis Retinol
CAS No.	22737-97-9
Molecular Formula	C₂₀H₃₀O
Molecular Weight	286.45 g/mol
Synonyms	(9Z)-Retinol; 9Z-Retinol; all-trans-Retinol isomer; neo b Vitamin A alcohol; Vitamin A1, (9Z)-; 9-cis-Vitamin A alcohol; (9Z,13Z)-Retinol (mixed isomers may be listed); 9,13-di-cis-Retinol
EINECS	Contact for details

Quality Control

Our 9-Cis Retinol is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and isomer specificity, to ensure it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store unopened vials at 2-8°C (refrigerated) or preferably at -20°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The material is hygroscopic (moisture-sensitive) and strictly light-sensitive (protect from all light exposure); all handling should be performed in a controlled environment with minimal exposure to air and light.

Specification

Item	Specification
Appearance	Yellow to pale yellow solid or oil
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0% (9-Cis Retinol)
Isomeric Purity (HPLC)	Reported on COA
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residue (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.