Description

Noncyclic Maleyl Chloride is a highly reactive bifunctional acid chloride derivative of maleic acid. This compound serves as a critical building block in organic synthesis, enabling the efficient introduction of the maleoyl functional group into target molecules. It is primarily utilized by manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for the synthesis of active ingredients, intermediates, and functional materials.

Application

• Pharmaceutical Intermediates: Key reagent in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, particularly for molecules requiring maleamic acid or maleimide structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where its reactivity facilitates the creation of novel bioactive compounds.
• Polymer & Resin Modification: Acts as a cross-linking agent or comonomer for producing specialty polymers, coatings, and adhesives with enhanced thermal or mechanical properties.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of reactive dyes and organic pigments, contributing to color fastness and molecular stability.
• Bioconjugation Chemistry: Useful for modifying proteins, peptides, and other biomolecules via reactions with amine groups to form stable maleimide linkages.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and material science applications.

Basic Information

Product Name	Noncyclic Maleyl Chloride
CAS No.	22542-53-6
Molecular Formula	C4H2Cl2O2
Molecular Weight	152.96 g/mol
Synonyms	Maleoyl Dichloride; Maleic Acid Dichloride; 2-Butenedioyl Dichloride; Dichloromaleic Anhydride; (Z)-2-Butenedioyl Dichloride; trans-Maleoyl Chloride; Maleoyl Chloride; NSC 8425
EINECS	245-031-8

Quality Control

Our Noncyclic Maleyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including assay, impurity profiling, and identity confirmation, to ensure it meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Maleic Anhydride	≤ 1.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.