Description

Diflunisal is a non-steroidal anti-inflammatory drug (NSAID) belonging to the salicylate class, known for its potent analgesic and anti-inflammatory properties. This high-purity active pharmaceutical ingredient (API) is critical for the development and manufacturing of effective pain management and anti-rheumatic medications. It is primarily required by pharmaceutical companies and research institutions engaged in the production of solid dosage forms and advanced drug delivery systems.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for the treatment of pain, osteoarthritis, and rheumatoid arthritis.
• Analgesic Formulations: Manufacture of tablets and capsules designed for long-lasting relief from mild to moderate pain.
• Anti-inflammatory Drugs: Production of anti-rheumatic drugs to reduce inflammation and swelling associated with musculoskeletal conditions.
• Clinical Research: Utilization as a reference standard or investigational compound in pharmacological and pharmacokinetic studies.
• Generic Drug Manufacturing: Sourcing for the production of bioequivalent generic versions of branded diflunisal products.
• Drug Delivery Systems: Research into novel formulations, including controlled-release and targeted delivery mechanisms.

Basic Information

Product Name	Diflunisal
CAS No.	22494-42-4
Molecular Formula	C13H8F2O3
Molecular Weight	250.20 g/mol
Synonyms	2',4'-Difluoro-4-hydroxy-3-biphenylcarboxylic acid; 5-(2,4-Difluorophenyl)salicylic acid; Dolobid; MK-647; Diflunisalum; UNII-56O48C7EN9
EINECS	245-025-8

Quality Control

Our Diflunisal is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide Certificates of Analysis (COA) detailing specifications for identity, purity, and impurities, with testing performed via validated methods such as HPLC, IR, and titration. The product can be supplied to meet various pharmacopeial standards, including USP and EP monographs, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.