Description

Piperazinone, 4-(2-Hydroxyethyl)-3,3-Dimethyl- (8Ci,9Ci) is a specialized heterocyclic building block with a unique piperazinone core functionalized with a hydroxyethyl group. This compound matters as a versatile intermediate for synthesizing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting the central nervous system (CNS) or acting as enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, or insecticides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate in the multi-step synthesis of high-value specialty chemicals for electronics, polymers, or advanced materials.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological studies and novel compound library generation.
• Chemical Biology Probes: Potential scaffold for developing molecular probes to study biological pathways and protein functions.

Basic Information

Product Name	Piperazinone, 4-(2-Hydroxyethyl)-3,3-Dimethyl- (8Ci,9Ci)
CAS No.	22492-72-4
Molecular Formula	C8H16N2O2
Molecular Weight	172.23 g/mol
Synonyms	4-(2-Hydroxyethyl)-3,3-dimethylpiperazin-2-one; 3,3-Dimethyl-4-(2-hydroxyethyl)-2-piperazinone; 1,4-Diaza-2-oxo-3,3-dimethyl-4-(2-hydroxyethyl)cyclohexane; 2-Piperazinone, 4-(2-hydroxyethyl)-3,3-dimethyl-; 4-(2-Hydroxyethyl)-3,3-dimethyl-2-piperazinone; 3,3-Dimethyl-4-(2-hydroxyethyl)piperazin-2-one
EINECS	Contact for details

Quality Control

Our Piperazinone, 4-(2-Hydroxyethyl)-3,3-Dimethyl- (8Ci,9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.