Description

2-[[(2R)-3-Decanoyloxy-2-Hydroxypropoxy]-Hydroxyphosphoryl]Oxyethyl-Trimethylazanium is a high-purity, synthetic phospholipid derivative, specifically a lysophosphatidylcholine analogue with a defined decanoyl chain. This compound is critical for researchers and formulators requiring precise molecular structure control in advanced lipid-based delivery systems. It serves as a key intermediate and functional excipient in the development of liposomes, lipid nanoparticles (LNPs), and other sophisticated drug delivery platforms for the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Excipient: As a component in the formulation of liposomes and lipid nanoparticles (LNPs) for mRNA, siRNA, and small molecule drug delivery.
• Biomembrane Research: Used in model membrane studies to investigate lipid bilayer properties, permeability, and protein-lipid interactions.
• Cell Culture & Transfection Reagents: An ingredient in specialized transfection reagents to enhance cellular uptake of nucleic acids.
• Cosmetic Formulations: Incorporated into high-end cosmetic products as an emulsifier and skin-conditioning agent for improved texture and delivery of active ingredients.
• Biochemical Tool: Serves as a substrate or standard in enzymatic assays for phospholipases and other lipid-metabolizing enzymes.
• Diagnostic Reagents: Used in the preparation of reagents for clinical diagnostics and analytical kits.

Basic Information

Product Name	2-[[(2R)-3-Decanoyloxy-2-Hydroxypropoxy]-Hydroxyphosphoryl]Oxyethyl-Trimethylazanium
CAS No.	22248-63-1
Molecular Formula	C20H42NO8P
Molecular Weight	455.52 g/mol
Synonyms	1-Decanoyl-2-hydroxy-sn-glycero-3-phosphocholine; LysoPC(10:0); 1-Capryloyl-2-hydroxy-sn-glycero-3-phosphocholine; (R)-2-Hydroxy-3-(decanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate; Lysophosphatidylcholine, decanoyl; L-α-Lysophosphatidylcholine, decanoyl; Decanoyl lysophosphatidylcholine; LPC(10:0/0:0)
EINECS	Contact for details

Quality Control

Our 2-[[(2R)-3-Decanoyloxy-2-Hydroxypropoxy]-Hydroxyphosphoryl]Oxyethyl-Trimethylazanium is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (R-configuration)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.