Description

(+-)-Ethambutol Dihydrochloride CAS NO 22196-75-4 is a high-purity pharmaceutical intermediate and active ingredient, specifically the dihydrochloride salt of the racemic mixture of ethambutol. This compound is of critical importance in the synthesis and formulation of anti-tuberculosis medications, where consistent quality and purity are paramount for efficacy and safety. It is primarily required by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in the development and production of treatments for mycobacterial infections.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of anti-tuberculosis drugs.
• Pharmaceutical Intermediate for the synthesis of Ethambutol-based formulations and combination therapies.
• Reference Standard in analytical laboratories for quality control and method validation.
• Research & Development for studying tuberculosis treatment mechanisms and developing new therapeutic agents.
• Fine Chemical Synthesis as a key building block for specialized chemical entities.

Basic Information

Product Name	(+-)-Ethambutol Dihydrochloride
CAS No.	22196-75-4
Molecular Formula	C10H24N2O2·2HCl
Molecular Weight	277.23 g/mol
Synonyms	Ethambutol HCl; Ethambutol Dihydrochloride; (2S,2'S)-2,2'-(Ethane-1,2-diyldiimino)dibutan-1-ol dihydrochloride; (±)-Ethambutol dihydrochloride; EMB dihydrochloride; Myambutol intermediate; (+/-)-Ethambutol hydrochloride; DS 17 dihydrochloride
EINECS	244-864-8

Quality Control

Our (+-)-Ethambutol Dihydrochloride is manufactured under strict quality systems. We provide material that meets high-purity standards suitable for pharmaceutical applications, with testing aligned with common pharmacopeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.