Description

Cyclopentanecarbonyl Chloride, 2-Oxo- (8Ci) CAS NO 22158-77-6 is a highly reactive acid chloride derivative of cyclopentanone, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized cyclopentane scaffold for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the 2-oxocyclopentane carbonyl moiety.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized cyclopentane rings, such as prostaglandin analogs and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the cyclopentanone structure imparts specific biological activity.
• Fine Chemical Production: Serves as a versatile reagent for producing specialty chemicals, including flavors, fragrances, and advanced materials.
• Academic & Industrial Research: A valuable tool in medicinal chemistry and process chemistry for exploring new synthetic routes and creating compound libraries.
• Peptide Mimetic & Prodrug Synthesis: Employed to introduce ketone-functionalized side chains or as a coupling agent in the design of peptide analogs and prodrugs.

Basic Information

Product Name	Cyclopentanecarbonyl Chloride, 2-Oxo- (8Ci)
CAS No.	22158-77-6
Molecular Formula	C6H7ClO2
Molecular Weight	146.57 g/mol
Synonyms	2-Oxocyclopentanecarbonyl Chloride; 2-Oxocyclopentane-1-carbonyl Chloride; Cyclopentanecarbonyl Chloride, 2-Oxo-; 1-(Chlorocarbonyl)cyclopentan-2-one; 2-Oxocyclopentylcarbonyl Chloride; 2-Ketocyclopentanecarbonyl Chloride; Cyclopentanone-2-carbonyl Chloride
EINECS	Contact for details

Quality Control

Our Cyclopentanecarbonyl Chloride, 2-Oxo- is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and IR & NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as water, alcohols, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.