Description

2-Chloro-3-Methyl-[1,3,2]Oxaza-Phospholidine is a specialized heterocyclic organophosphorus compound that serves as a versatile building block in advanced chemical synthesis. Its unique structure, featuring a reactive phosphorus-chlorine bond within a constrained ring system, makes it a critical intermediate for introducing functional phosphorus motifs. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer agents, particularly those targeting nucleotide metabolism.
• Agrochemical Synthesis: Building block for creating advanced insecticides, herbicides, and plant growth regulators with specific modes of action.
• Ligand & Catalyst Development: Used to prepare chiral phosphine and phosphoramidite ligands for asymmetric catalysis in fine chemical production.
• Polymer Modification: Acts as a reactive monomer or cross-linking agent for flame-retardant polymers and specialty resins.
• Chemical Research: Valuable reagent in academic and industrial R&D for exploring new organophosphorus chemistry and material science applications.

Basic Information

Product Name	2-Chloro-3-Methyl-[1,3,2]Oxaza-Phospholidine
CAS No.	22082-71-9
Molecular Formula	C3H7ClNOP
Molecular Weight	139.52 g/mol
Synonyms	2-Chloro-3-methyl-1,3,2-oxazaphospholidine; 3-Methyl-2-chloro-1,3,2-oxazaphospholidine; 2-Chloro-3-methyl-2-oxo-1,3,2-oxazaphospholidine; 2-Chloro-3-methyl-2-oxo-1,3,2λ5-oxazaphospholidine; Methylchlorooxazaphospholidine; OXA-PHOS Precursor; Phosphoramidous dichloride derivative
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Methyl-[1,3,2]Oxaza-Phospholidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets exacting R&D and production standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.