Description

Piperazine-1,4-Dicarbonitrile is a versatile heterocyclic building block featuring two nitrile functional groups on a piperazine core. This compound matters for its role as a key precursor in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. Industries that need it include pharmaceutical R&D for creating novel active ingredients, agrochemical manufacturers developing new crop protection agents, and specialty chemical producers synthesizing advanced polymers and ligands.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of piperazine-based drug candidates, including potential antivirals, antifungals, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, insecticides, and fungicides where the piperazine moiety contributes to biological activity.
• Ligand and Chelator Precursor: Serves as a starting material for creating complexing agents and ligands used in catalysis and metal ion sequestration.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers, such as polyamides and polyimides, with high thermal stability.
• Organic Synthesis Reagent: Employed in various organic transformations, including nucleophilic substitution and cyclization reactions, to construct nitrogen-containing heterocycles.
• Research & Development: Utilized in academic and industrial R&D laboratories for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	Piperazine-1,4-Dicarbonitrile
CAS No.	22005-33-0
Molecular Formula	C6H6N4
Molecular Weight	134.14 g/mol
Synonyms	1,4-Dicyanopiperazine; Piperazine-1,4-dicarbonitrile; 1,4-Piperazinedicarbonitrile; Piperazine-1,4-dicarboxamide dinitrile; 1,4-Piperazinedicarboxamide dinitrile; 1,4-Dicyano-piperazine; 2,5-Diazabicyclo[2.2.2]octane-1,4-dicarbonitrile (bridged structure); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Piperazine-1,4-Dicarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters such as assay (by HPLC), identification (IR), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.