Description

2-Hydroxy-3-(Phosphonooxy)Propyl (9Z,12Z)-Octadeca-9,12-Dienoate is a specialized phospholipid derivative, also known as a phosphorylated linoleic acid ester. This compound is valued for its unique amphiphilic structure, combining a bioactive fatty acid moiety with a phosphate ester group, which imparts surfactant and membrane-modifying properties. It is primarily utilized in advanced research and development within the pharmaceutical, nutraceutical, and specialty chemical industries for applications in drug delivery systems, lipid biochemistry, and as a functional intermediate.

Application

• Pharmaceutical Research: As a key intermediate or functional excipient in the development of liposomal and nanoparticle-based drug delivery systems to enhance bioavailability.
• Biochemical Studies: Used as a substrate or model compound in enzymatic studies related to phospholipid metabolism and cell membrane biophysics.
• Nutraceutical Formulations: Potential incorporation into advanced lipid-based supplements targeting cellular health and membrane fluidity.
• Specialty Surfactants: Serves as a building block for synthesizing novel, biodegradable surfactants and emulsifiers with specific functional properties.
• Cosmetic Actives: Investigated for use in high-end cosmetic formulations for skin barrier repair and delivery of active ingredients.
• Material Science: As a monomer or additive in the creation of functional polymers and biomaterials with tailored surface characteristics.

Basic Information

Product Name	2-Hydroxy-3-(Phosphonooxy)Propyl (9Z,12Z)-Octadeca-9,12-Dienoate
CAS No.	22002-88-6
Molecular Formula	C21H39O7P
Molecular Weight	434.50 g/mol
Synonyms	Linoleic Acid 2-Hydroxy-3-Phosphonooxypropyl Ester; Phosphorylated Glyceryl Linoleate; 3-Phosphono-2-hydroxypropyl Linoleate; 2-Hydroxy-3-phosphonooxypropyl Linoleate; Glyceryl Phosphoryl Linoleate; (9Z,12Z)-2-Hydroxy-3-(phosphonooxy)propyl octadeca-9,12-dienoate; Linoleoyl Glycerophosphoric Acid; 1-Linoleoyl-2-hydroxy-sn-glycero-3-phosphate (related structure)
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-(Phosphonooxy)Propyl (9Z,12Z)-Octadeca-9,12-Dienoate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and structural confirmation, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request. We support development projects by offering material tailored to research-grade or cGMP standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.