Description

(1S,3Aα,8R)-Octahydro-1,7Aα-Dimethyl-5α-Isopropyl-1,4β-Methano-1H-Inden-8-Ol CAS NO 21966-93-8 is a high-purity, stereochemically defined sesquiterpene alcohol derivative, valued for its unique and rigid molecular framework. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecules with precise stereochemistry. It is essential for research and development in the pharmaceutical, agrochemical, and fine chemical sectors, where its structural motifs are leveraged to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in steroid-mimetic and terpenoid-based therapeutic agents.
• Agrochemical Research: Used in developing new generation pesticides and herbicides, where its complex hydrocarbon skeleton provides unique biological activity.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthesizing high-value, natural-identical aroma chemicals with woody, amber, or musk characteristics.
• Material Science: Investigated as a monomer or cross-linking agent for creating specialty polymers with specific thermal or mechanical properties.
• Catalyst & Ligand Development: Its rigid, three-dimensional structure makes it a candidate for designing novel chiral ligands in asymmetric catalysis.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological studies in total synthesis and natural product chemistry.

Basic Information

Product Name	(1S,3Aα,8R)-Octahydro-1,7Aα-Dimethyl-5α-Isopropyl-1,4β-Methano-1H-Inden-8-Ol
CAS No.	21966-93-8
Molecular Formula	C15H26O
Molecular Weight	222.37 g/mol
Synonyms	8-Hydroxy-1,7aα-dimethyl-5α-(propan-2-yl)-1,2,3,3aα,4,5,6,7-octahydro-1,4-methano-1H-indene; (1S,3aR,4S,7S,7aR)-Octahydro-4,7-dimethyl-1-(propan-2-yl)-1H-4,7-methanoinden-1-ol; 1,4-Methano-1H-inden-8-ol octahydro derivative; Cedrol isomer; Sesquiterpene alcohol intermediate; Chiral decalin derivative
EINECS	Contact for details

Quality Control

Our (1S,3Aα,8R)-Octahydro-1,7Aα-Dimethyl-5α-Isopropyl-1,4β-Methano-1H-Inden-8-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.