Description

(13α,17R)-21,23-Epoxy-7α,17-Dihydroxy-4,4,8-Trimethyl-3-Oxo-16,17-Seco-24-Nor-5α-Chola-1,14,20,22-Tetren-16-Oic Acid 16,17-Lactone is a high-purity, complex steroidal lactone derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel bioactive molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for its unique structural framework.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Research & Development: Used as a reference standard and a starting material in medicinal chemistry for drug discovery programs.
• Biochemical Research: Investigated for its potential biological activity and interactions with steroid hormone receptors.
• Fine Chemical Synthesis: Serves as a sophisticated chiral building block for constructing complex natural product analogs and specialty chemicals.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target molecules.

Basic Information

Product Name	(13α,17R)-21,23-Epoxy-7α,17-Dihydroxy-4,4,8-Trimethyl-3-Oxo-16,17-Seco-24-Nor-5α-Chola-1,14,20,22-Tetren-16-Oic Acid 16,17-Lactone
CAS No.	21963-96-2
Molecular Formula	C24H28O5
Molecular Weight	396.48 g/mol
Synonyms	16,17-Seco-24-nor-5α-chola-1,14,20,22-tetraene-16,17-lactone, 21,23-epoxy-7α,17-dihydroxy-4,4,8-trimethyl-3-oxo-, (13α,17R)-; 21,23-Epoxy-7α,17-dihydroxy-4,4,8-trimethyl-3-oxo-16,17-seco-24-nor-5α-chola-1,14,20,22-tetraen-16-oic acid γ-lactone; 24-Nor-5α-chola-1,14,20,22-tetraene-16,17-lactone derivative; Steroidal Lactone Derivative CAS 21963-96-2
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing comprehensive analytical results from techniques including HPLC, NMR, and mass spectrometry. We adhere to a cGMP-compliant quality management system to ensure reliability for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.