Description

5-Bromo-3-Chloropyrazin-2-Ol CAS NO 21943-17-9 is a high-purity halogenated pyrazine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its unique structure, featuring both bromine and chlorine substituents, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyrazine core.
• Material Science Research: Serves as a precursor for the synthesis of functionalized heterocyclic compounds used in organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects requiring specific halogenated pyrazine motifs.

Basic Information

Product Name	5-Bromo-3-Chloropyrazin-2-Ol
CAS No.	21943-17-9
Molecular Formula	C4H2BrClN2O
Molecular Weight	209.43 g/mol
Synonyms	5-Bromo-3-chloro-2-hydroxypyrazine; 3-Chloro-5-bromopyrazin-2-ol; 2-Pyrazinol, 5-bromo-3-chloro-; 5-Bromo-3-chloro-1,4-dihydropyrazin-2-one; 5-Bromo-3-chloro-2(1H)-pyrazinone; 21943-17-9; 5-Bromo-3-chloropyrazin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Chloropyrazin-2-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP standards where applicable, ensuring the material meets the stringent requirements for research and development use in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.