Description

2-Amino-5-Bromo-3-Chloropyrazine is a high-purity halogenated pyrazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for constructing complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for antiviral, anticancer, and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, ligands, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold or linker in the design of molecular probes, inhibitors, and tool compounds for biological research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	2-Amino-5-Bromo-3-Chloropyrazine
CAS No.	21943-13-5
Molecular Formula	C4H3BrClN3
Molecular Weight	208.44 g/mol
Synonyms	5-Bromo-3-chloro-2-pyrazinamine; 3-Chloro-5-bromo-2-pyrazinamine; 2-Pyrazinamine, 5-bromo-3-chloro-; 5-Bromo-3-chloropyrazin-2-amine; 2-Amino-3-chloro-5-bromopyrazine; 3-Chloro-5-bromopyrazin-2-amine; 5-Bromo-3-chloro-2-aminopyrazine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Bromo-3-Chloropyrazine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.