Description

2-Amino-3-Bromopyrazine is a versatile brominated pyrazine derivative, a key heterocyclic building block prized for its reactivity in cross-coupling and substitution reactions. Its primary value lies in enabling the synthesis of complex molecules for advanced research and development. This high-purity intermediate is essential for pharmaceutical chemists and agrochemical researchers developing new active ingredients, as well as for material scientists working on functional organic compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for creating organic electronic materials, ligands for catalysts, and specialty polymers.
• Chemical Research: Employed in academic and industrial R&D for constructing complex heterocyclic frameworks via Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Ligand Preparation: Useful for synthesizing novel nitrogen-containing ligands used in coordination chemistry and homogeneous catalysis.

Basic Information

Item	Detail
Product Name	2-Amino-3-Bromopyrazine
CAS No.	21943-12-4
Molecular Formula	C4H4BrN3
Molecular Weight	173.99 g/mol
Synonyms	3-Bromo-2-pyrazinamine; 3-Bromopyrazin-2-amine; 2-Pyrazinamine, 3-bromo-; 2-Amino-3-bromopyrazine; 3-Bromo-2-aminopyrazine; 2-Amino-3-bromo-1,4-diazine
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Bromopyrazine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.