Description

5-[(2-Chloroethyl)Sulphonyl]Bicyclo[2.2.1]Heptane-2-Carbonyl Chloride is a specialized, high-purity organic intermediate featuring a reactive bicyclic norbornane core functionalized with both a sulfonyl chloride and an acid chloride group. This compound matters for its role as a critical building block in the synthesis of complex molecules, offering unique steric and electronic properties for advanced material and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting the central nervous system (CNS) or possessing complex polycyclic architectures.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides where the norbornane scaffold can impart favorable biological activity and environmental stability.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent for creating high-performance polymers with specific thermal, mechanical, or chemical resistance properties.
• Ligand & Catalyst Development: Employed in the preparation of specialized chiral ligands or organometallic catalysts for asymmetric synthesis applications.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme mechanisms or protein interactions due to its dual-reactive sites, allowing for specific labeling.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical industry.

Basic Information

Product Name	5-[(2-Chloroethyl)Sulphonyl]Bicyclo[2.2.1]Heptane-2-Carbonyl Chloride
CAS No.	21912-24-3
Molecular Formula	C10H12Cl2O3S
Molecular Weight	283.17 g/mol
Synonyms	2-(2-Chloroethanesulfonyl)bicyclo[2.2.1]heptane-5-carbonyl chloride; Bicyclo[2.2.1]heptane-2-carbonyl chloride, 5-[(2-chloroethyl)sulfonyl]-; 5-(2-Chloroethylsulfonyl)bicyclo[2.2.1]heptane-2-carbonyl chloride; 5-[(2-Chloroethyl)sulfonyl]-2-norbornanecarbonyl chloride; Norbornane carbonyl chloride derivative; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 5-[(2-Chloroethyl)Sulphonyl]Bicyclo[2.2.1]Heptane-2-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.