Description

3-Bromo-2-Methyl Benzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value proposition lies in enabling the efficient introduction of the 3-bromo-2-methylbenzoyl moiety, a key structural motif for modulating biological activity and material properties. This intermediate is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated benzamide or ester functionalities.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the bromine and methyl substituents influence potency and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Polymer and Material Science: Employed in the synthesis of monomers for high-performance polymers, liquid crystals, and organic electronic materials.
• Dyestuff and Pigment Manufacturing: Acts as an intermediate for producing complex organic dyes and pigments with specific color and stability properties.
• Custom Synthesis and Contract Research: A valuable reagent for research organizations and CDMOs (Contract Development and Manufacturing Organizations) engaged in custom molecule synthesis.

Basic Information

Item	Details
Product Name	3-Bromo-2-Methyl Benzoyl Chloride
CAS No.	21900-48-1
Molecular Formula	C9H8BrClO
Molecular Weight	247.52 g/mol
Synonyms	2-Methyl-3-bromobenzoyl chloride; 3-Bromo-o-toluoyl chloride; 3-Bromo-2-methylbenzoic acid chloride; (3-Bromo-2-methylphenyl)carbonyl chloride; 3-Bromo-2-methylbenzoyl chloride; 2-Methyl-3-bromobenzoic acid chloride; α,3-Dibromo-o-toluoyl chloride (less common); Benzoyl chloride, 3-bromo-2-methyl-
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Methyl Benzoyl Chloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are available for every shipment. We are committed to meeting the stringent requirements of cGMP and ISO 9001 standards where applicable for intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.