Description

1-(4-Ethoxybenzyl)Piperazine is a versatile organic building block and intermediate of significant importance in advanced chemical synthesis. This compound matters for its role as a key precursor in the development of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals. Industries such as pharmaceutical R&D, agrochemical manufacturing, and fine chemical production require this high-purity intermediate for creating novel molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its piperazine moiety.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Fine Chemical Production: Employed in the manufacture of complex dyes, pigments, and other performance chemicals.
• Academic and Industrial Research: A valuable reagent for medicinal chemistry programs and chemical biology studies in R&D laboratories.
• Polymer Modification: Can be utilized to introduce functional groups into polymer chains for specialty material applications.

Basic Information

Product Name	1-(4-Ethoxybenzyl)Piperazine
CAS No.	21867-70-9
Molecular Formula	C13H20N2O
Molecular Weight	220.31 g/mol
Synonyms	1-[(4-Ethoxyphenyl)methyl]piperazine; 4-Ethoxybenzylpiperazine; N-(4-Ethoxybenzyl)piperazine; 1-(4-Ethoxybenzyl)piperazine; 21867-70-9; 4-Ethoxy-α-(piperazin-1-ylmethyl)benzene; 1-(p-Ethoxybenzyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-(4-Ethoxybenzyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.