Description

1-Methyl-10-(14,15-Dihydroeburnamenine-14-Yl)-11-Hydroxy-1,2-Dihydro-2β,16-(Epoxymethano)Akuammilan-17-Oic Acid Methyl Ester is a complex indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate or reference standard for the development of novel therapeutic agents, particularly those targeting neurological pathways. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of complex alkaloid-based drug candidates.
• Biochemical Research: Used as a reference standard or probe in studies investigating alkaloid biosynthesis, receptor binding, or enzymatic activity.
• Medicinal Chemistry: Provides a core scaffold for structure-activity relationship (SAR) studies aimed at discovering new neuroactive or other pharmacologically active compounds.
• Analytical Standard: Employed in analytical laboratories for method development, calibration, and quality control of related substances in pharmaceutical products.
• Academic Research: Utilized in university and institutional labs for synthetic methodology development and the total synthesis of natural products.

Basic Information

Product Name	1-Methyl-10-(14,15-Dihydroeburnamenine-14-Yl)-11-Hydroxy-1,2-Dihydro-2β,16-(Epoxymethano)Akuammilan-17-Oic Acid Methyl Ester
CAS No.	21851-24-1
Molecular Formula	C43H50N2O5
Molecular Weight	674.9 g/mol
Synonyms	Vincamajine; Vincamagine; (2β,16α,19α)-1-Methyl-10-[(14,15-dihydro-14-eburnameninyl]-11-hydroxy-2,16-methano-16H-1,19-epoxyakuammilan-17-carboxylic acid methyl ester; Methyl (2β,16α,19α)-1-methyl-10-[(14,15-dihydro-14-eburnameninyl]-11-hydroxy-2,16-methano-16H-1,19-epoxyakuammilan-17-carboxylate; 16-Epivincamajine; 16-Epivincamagine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system supports the needs of research and development requiring high-purity reference materials and intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.